Dementia risk with antihypertensive use and blood pressure variability: A cohort study.
Identifieur interne : 002117 ( Main/Exploration ); précédent : 002116; suivant : 002118Dementia risk with antihypertensive use and blood pressure variability: A cohort study.
Auteurs : Phillip J. Tully [France] ; Jean-François Dartigues [France] ; Stephanie Debette [France] ; Catherine Helmer [France] ; Sylvaine Artero [France] ; Christophe Tzourio [France]Source :
- Neurology [ 1526-632X ] ; 2016.
Descripteurs français
- KwdFr :
- Antihypertenseurs (usage thérapeutique), Diurétiques (usage thérapeutique), Démence (physiopathologie), Démence (épidémiologie), Femelle, France (épidémiologie), Humains, Inhibiteurs des canaux calciques (usage thérapeutique), Mâle, Pression sanguine (physiologie), Sujet âgé, Sujet âgé de 80 ans ou plus, Études prospectives.
- MESH :
- physiologie : Pression sanguine.
- physiopathologie : Démence.
- usage thérapeutique : Antihypertenseurs, Diurétiques, Inhibiteurs des canaux calciques.
- épidémiologie : Démence, France.
- Femelle, Humains, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Études prospectives.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antihypertensive Agents, Calcium Channel Blockers, Diuretics.
- epidemiology : Dementia, France.
- physiology : Blood Pressure.
- physiopathology : Dementia.
- Aged, Aged, 80 and over, Female, Humans, Male, Prospective Studies.
Abstract
To determine the association between discrete antihypertensive drug classes and incident dementia controlling for blood pressure variability (BPV) in the preceding 4 years.
DOI: 10.1212/WNL.0000000000002946
PubMed: 27402894
Affiliations:
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Le document en format XML
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<author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stephanie" last="Debette">Stephanie Debette</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Artero, Sylvaine" sort="Artero, Sylvaine" uniqKey="Artero S" first="Sylvaine" last="Artero">Sylvaine Artero</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France. christophe.tzourio@u-bordeaux.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Dementia risk with antihypertensive use and blood pressure variability: A cohort study.</title>
<author><name sortKey="Tully, Phillip J" sort="Tully, Phillip J" uniqKey="Tully P" first="Phillip J" last="Tully">Phillip J. Tully</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Dartigues, Jean Francois" sort="Dartigues, Jean Francois" uniqKey="Dartigues J" first="Jean-François" last="Dartigues">Jean-François Dartigues</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stephanie" last="Debette">Stephanie Debette</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
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<author><name sortKey="Artero, Sylvaine" sort="Artero, Sylvaine" uniqKey="Artero S" first="Sylvaine" last="Artero">Sylvaine Artero</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name>
<affiliation wicri:level="3"><nlm:affiliation>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux, France. christophe.tzourio@u-bordeaux.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>From Neuroepidemiology, UMR897 (P.J.T., S.D., C.T.), and Epidemiology and Biostatistics, Institut National de la Santé et de la Recherche Médicale U897 (J.-F.D., C.H.), University of Bordeaux, France; Freemasons Foundation Centre for Men's Health (P.J.T.), Discipline of Medicine, School of Medicine, The University of Adelaide, Australia; Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Neurology (S.D.), Framingham Heart Study, Boston University School of Medicine, MA; INSERM U1061 (S.A.), La Colombière Hospital, University of Montpellier UM1; and INSERM (P.J.T., C.T.), Neuroepidemiology, UMR897, Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Antihypertensive Agents (therapeutic use)</term>
<term>Blood Pressure (physiology)</term>
<term>Calcium Channel Blockers (therapeutic use)</term>
<term>Dementia (epidemiology)</term>
<term>Dementia (physiopathology)</term>
<term>Diuretics (therapeutic use)</term>
<term>Female</term>
<term>France (epidemiology)</term>
<term>Humans</term>
<term>Male</term>
<term>Prospective Studies</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Antihypertenseurs (usage thérapeutique)</term>
<term>Diurétiques (usage thérapeutique)</term>
<term>Démence (physiopathologie)</term>
<term>Démence (épidémiologie)</term>
<term>Femelle</term>
<term>France (épidémiologie)</term>
<term>Humains</term>
<term>Inhibiteurs des canaux calciques (usage thérapeutique)</term>
<term>Mâle</term>
<term>Pression sanguine (physiologie)</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antihypertensive Agents</term>
<term>Calcium Channel Blockers</term>
<term>Diuretics</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Dementia</term>
<term>France</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Pression sanguine</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Blood Pressure</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Démence</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dementia</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antihypertenseurs</term>
<term>Diurétiques</term>
<term>Inhibiteurs des canaux calciques</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Démence</term>
<term>France</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Prospective Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Études prospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">To determine the association between discrete antihypertensive drug classes and incident dementia controlling for blood pressure variability (BPV) in the preceding 4 years.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Aquitaine</li>
<li>Nouvelle-Aquitaine</li>
</region>
<settlement><li>Bordeaux</li>
</settlement>
</list>
<tree><country name="France"><region name="Nouvelle-Aquitaine"><name sortKey="Tully, Phillip J" sort="Tully, Phillip J" uniqKey="Tully P" first="Phillip J" last="Tully">Phillip J. Tully</name>
</region>
<name sortKey="Artero, Sylvaine" sort="Artero, Sylvaine" uniqKey="Artero S" first="Sylvaine" last="Artero">Sylvaine Artero</name>
<name sortKey="Dartigues, Jean Francois" sort="Dartigues, Jean Francois" uniqKey="Dartigues J" first="Jean-François" last="Dartigues">Jean-François Dartigues</name>
<name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stephanie" last="Debette">Stephanie Debette</name>
<name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name>
<name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name>
</country>
</tree>
</affiliations>
</record>
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